CD276 anticorps (AA 29-245) (Biotin)

N° du produit ABIN7093001

Cet anticorps anti-CD276 Monoclonal Lapin conjugué à Biotin (Clone DM53) (ABIN7093001) détecte spécifiquement CD276 dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CD276 anticorps (AA 29-245) (Biotin) (ABIN7093001)

Antigène: CD276

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD276 est conjugé à/à la Biotin

Application: Flow Cytometry (FACS)

Clone: DM53

Détail du produit anti-CD276 anticorps (Biotin)

Épitope: AA 29-245

Fonction: Biotinylated Anti-B7-H3 antibody(DM53), Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Immunogène: Recombinant human  B7H3(Leu29-Pro245) (ABIN6961085) produced by using human HEK293 cells

Isotype: IgG

Information d'application

Indications d'application: Flow Cyt 1:1000

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détails sur CD276

Antigène: CD276

Autre désignation: B7-H3

Sujet: Synonyms:B7-H3, CD276, B7 homolog 3, B7H3
Description:The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 57 kDa

ID gène: 80381

UniProt: Q5ZPR3

Pathways: Cancer Immune Checkpoints