CD276 anticorps (AA 29-245) (Biotin)

N° du produit ABIN7093001

Détail du produit anti-CD276 anticorps (Biotin)

Antigène: CD276

Épitope: AA 29-245

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD276 est conjugé à/à la Biotin

Application: ELISA, Flow Cytometry (FACS)

Purification: Purified from cell culture supernatant by affinity chromatography

Immunogène: Recombinant human  B7H3(Leu29-Pro245) (ABIN6961085) produced by using human HEK293 cells

Clone: DM53

Isotype: IgG

Information d'application

Indications d'application: ELISA 1/5000-10000,Flow Cyt  1/100

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: 50 % Glycerol, PBS, pH 7.4, 0.1 % BSA,0.1 % Procline 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détails sur CD276

Antigène: CD276

Autre désignation: B7-H3 (CD276 Produits)

Synonymes: anticorps sc:d0645, anticorps zgc:158279, anticorps 6030411F23Rik, anticorps AU016588, anticorps B7RP-2, anticorps B7h3, anticorps B7H3, anticorps 4Ig-B7-H3, anticorps B7-H3, anticorps CD276 molecule, anticorps CD276 molecule S homeolog, anticorps CD276 antigen, anticorps Cd276 molecule, anticorps CD276, anticorps cd276.S, anticorps cd276, anticorps Cd276

Sujet: Synonyms:B7-H3, CD276, B7 homolog 3, B7H3
Description:The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 57 kDa

ID gène: 80381

UniProt: Q5ZPR3

Pathways: Cancer Immune Checkpoints