BPGM anticorps

N° du produit ABIN7111094

L’anticorps Lapin Polyclonal anti-BPGM a été validé pour WB, ELISA et IHC. Il convient pour détecter BPGM dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour BPGM anticorps (ABIN7111094)

Antigène: BPGM (2,3-bisphosphoglycerate Mutase (BPGM))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BPGM est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-BPGM anticorps

Fonction: BPGM antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: 2, 3-bisphosphoglycerate mutase

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur BPGM

Antigène: BPGM (2,3-bisphosphoglycerate Mutase (BPGM))

Autre désignation: BPGM

Sujet:

Synonyms: Bisphosphoglycerate mutase (BPGM)|2,3-bisphosphoglycerate mutase, erythrocyte|2,3-bisphosphoglycerate synthase|2,3-diphosphoglycerate mutase (DPGM)|BPG-dependent PGAM|BPGM

Background: 2, 3-diphosphoglycerate (2, 3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2, 3-DPG synthesis via its synthetase activity, and 2, 3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Poids moléculaire: 30 kDa

ID gène: 669

UniProt: P07738