ABHD2 anticorps

N° du produit ABIN7111166

L’anticorps Lapin Polyclonal anti-ABHD2 a été validé pour ELISA, WB et IHC. Il convient pour détecter ABHD2 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ABHD2 anticorps (ABIN7111166)

Antigène: ABHD2 (Abhydrolase Domain Containing 2 (ABHD2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABHD2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-ABHD2 anticorps

Fonction: ABHD2 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: abhydrolase domain containing 2

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur ABHD2

Antigène: ABHD2 (Abhydrolase Domain Containing 2 (ABHD2))

Autre désignation: ABHD2

Sujet:

Synonyms: Monoacylglycerol lipase ABHD2|2-arachidonoylglycerol hydrolase|Abhydrolase domain-containing protein 2|Acetylesterase|Lung alpha/beta hydrolase 2|Progesterone-sensitive lipase|Protein PHPS1-2|ABHD2|LABH2

Background: Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol(AG) from cell membrane(PubMed:26989199). Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol(1AG) and 2-arachidonoylglycerol(2AG) to glycerol and arachidonic acid(AA)(PubMed:26989199). Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2AG, an inhibitor of the sperm calcium channel CatSper, leading to calcium influx via CatSper and sperm activation(PubMed:26989199). May also play a role in smooth muscle cells migration(By similarity).

Poids moléculaire: 48 kDa

ID gène: 11057

UniProt: P08910