ACPP anticorps (AA 27-373)

N° du produit ABIN7111188

Cet anticorps anti-ACPP est un anticorps Souris Monoclonal détectant ACPP dans WB, IHC et ELISA. Adapté pour Humain et Rat.

Aperçu rapide pour ACPP anticorps (AA 27-373) (ABIN7111188)

Antigène: ACPP (Acid Phosphatase, Prostate (ACPP))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ACPP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 8D6

Détail du produit anti-ACPP anticorps

Épitope: AA 27-373

Fonction: ACP3 antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 27-373aa

Immunogen: acid phosphatase, prostate

Isotype: IgG2a

Information d'application

Indications d'application: WB: 1:200-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur ACPP

Antigène: ACPP (Acid Phosphatase, Prostate (ACPP))

Autre désignation: ACP3

Sujet:

Synonyms: Prostatic acid phosphatase (PAP)|5'-nucleotidase (5'-NT)|Acid phosphatase 3|Ecto-5'-nucleotidase|Protein tyrosine phosphatase ACP3|Thiamine monophosphatase (TMPase)|PAPf39|ACP3|ACPP

Background: A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions( pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma. Isoform 2: the cellular form also has ecto-5'-nucleotidase activity in dorsal root ganglion(DRG) neurons. Generates adenosine from AMP which acts as a pain suppressor. Acts as a tumor suppressor of prostate cancer through dephosphorylation of ERBB2 and deactivation of MAPK-mediated signaling.

Poids moléculaire: 48 kDa

ID gène: 55

UniProt: P15309

Pathways: Synaptic Membrane, Ribonucleoside Biosynthetic Process