alpha Actinin 4 anticorps (AA 720-911)

N° du produit ABIN7111233

Cet anticorps anti-alpha Actinin 4 est un anticorps Lapin Polyclonal détectant alpha Actinin 4 dans WB, ELISA, IHC, IP, IF et FACS. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour alpha Actinin 4 anticorps (AA 720-911) (ABIN7111233)

Antigène: alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp alpha Actinin 4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-alpha Actinin 4 anticorps

Épitope: AA 720-911

Fonction: ACTN4 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 720-911aa

Immunogen: actinin, alpha 4

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IHC: 1:20-1:200, IP: 1:500-1:5000, IF: 1:10-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur alpha Actinin 4

Antigène: alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))

Autre désignation: ACTN4

Sujet:

Synonyms: Alpha-actinin-4|Non-muscle alpha-actinin 4|ACTN4

Background: F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein(Probable). Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation(PubMed:15772161). Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions(By similarity). May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA(PubMed:22351778).

Poids moléculaire: 105 kDa

ID gène: 81

UniProt: O43707

Pathways: Proton Transport