ARL2 anticorps

N° du produit ABIN7111380

Cet anticorps anti-ARL2 est un anticorps Lapin Polyclonal détectant ARL2 dans WB, ELISA et IHC. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour ARL2 anticorps (ABIN7111380)

Antigène: ARL2 (ADP-Ribosylation Factor-Like 2 (ARL2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARL2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-ARL2 anticorps

Fonction: ARL2 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: ADP-ribosylation factor-like 2

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur ARL2

Antigène: ARL2 (ADP-Ribosylation Factor-Like 2 (ARL2))

Autre désignation: ARL2

Sujet:

Synonyms: ADP-ribosylation factor-like protein 2|ARL2

Background: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors(GEF) and GTPase-activating proteins(GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction. Participates in association with TBCD, in the disassembly of the apical junction complexes. Antagonizes the effect of TBCD on epithelial cell detachment and tight and adherens junctions disassembly. Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. Component of a regulated secretory pathway involved in Ca(2+)-dependent release of acetylcholine. Required for normal progress through the cell cycle.

Poids moléculaire: 21-25 kDa

ID gène: 402

UniProt: P36404

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location