ARL3 anticorps
Aperçu rapide pour ARL3 anticorps (ABIN7111382)
Antigène
Voir toutes ARL3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Fonction
- ARL3 antibody
-
Purification
- Immunogen affinity purified
-
Pureté
- ≥95 % as determined by SDS-PAGE
-
Immunogène
- ADP-ribosylation factor-like 3
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- -20°C for 12 months
-
Date de péremption
- 12 months
-
-
- ARL3 (ADP-Ribosylation Factor-Like 3 (ARL3))
-
Autre désignation
- ARL3
-
Sujet
-
Synonyms: ADP-ribosylation factor-like protein 3|ARL3|ARFL3
Background: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors(GEF) and GTPase-activating proteins(GAP). Required for normal cytokinesis and cilia signaling. Requires assistance from GTPase-activating proteins(GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms. Required for targeting proteins such as NPHP3 to the ciliary membrane by releasing myristoylated NPHP3 from UNC119B cargo adapter into the cilium. Does not act as an allosteric activator of the cholera toxin catalytic subunit.
-
Poids moléculaire
- 20 kDa
-
ID gène
- 403
-
UniProt
- P36405
Antigène
-