AFF4 anticorps

N° du produit ABIN7111408

Cet anticorps Lapin Polyclonal détecte spécifiquement AFF4 dans WB, ELISA et IP. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour AFF4 anticorps (ABIN7111408)

Antigène: AFF4 (AF4/FMR2 Family, Member 4 (AFF4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AFF4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Détail du produit anti-AFF4 anticorps

Fonction: AFF4 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: AF4/FMR2 family, member 4

Isotype: IgG

Information d'application

Indications d'application: WB: 1:200-1:2000, IP: 1:200-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur AFF4

Antigène: AFF4 (AF4/FMR2 Family, Member 4 (AFF4))

Autre désignation: AFF4

Sujet:

Synonyms: AF4/FMR2 family member 4|ALL1-fused gene from chromosome 5q31 protein (Protein AF-5q31)|Major CDK9 elongation factor-associated protein|AFF4|AF5Q31|MCEF

Background: Key component of the super elongation complex(SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. In the SEC complex, AFF4 acts as a central scaffold that recruits other factors through direct interactions with ELL proteins(ELL, ELL2 or ELL3) and the P-TEFb complex. In case of infection by HIV-1 virus, the SEC complex is recruited by the viral Tat protein to stimulate viral gene expression.

Poids moléculaire: 150 kDa

ID gène: 27125

UniProt: Q9UHB7