ARRDC3 anticorps
Aperçu rapide pour ARRDC3 anticorps (ABIN7111730)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- ARRDC3 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- arrestin domain containing 3
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:1000, IF: 1:10-1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- ARRDC3 (Arrestin Domain Containing 3 (ARRDC3))
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Autre désignation
- ARRDC3
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Sujet
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Synonyms: Arrestin domain-containing protein 3|TBP-2-like inducible membrane protein (TLIMP)|ARRDC3|KIAA1376
Background: Adapter protein that plays a role in regulating cell-surface expression of adrenergic receptors and probably also other G protein-coupled receptors(PubMed:20559325, PubMed:21982743, PubMed:23208550). Plays a role in NEDD4-mediated ubiquitination and endocytosis af activated ADRB2 and subsequent ADRB2 degradation(PubMed:20559325, PubMed:23208550). May recruit NEDD4 to ADRB2(PubMed:20559325). Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes(PubMed:23208550).
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Poids moléculaire
- 46 kDa
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ID gène
- 57561
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UniProt
- Q96B67
Antigène
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