Aryl Hydrocarbon Receptor anticorps (AA 12-215)

N° du produit ABIN7111734

Cet anticorps anti-Aryl Hydrocarbon Receptor est un anticorps Lapin Polyclonal détectant Aryl Hydrocarbon Receptor dans WB, IHC, ELISA et IP. Adapté pour Humain et Souris.

Aperçu rapide pour Aryl Hydrocarbon Receptor anticorps (AA 12-215) (ABIN7111734)

Antigène: Aryl Hydrocarbon Receptor (AHR)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aryl Hydrocarbon Receptor est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Détail du produit anti-Aryl Hydrocarbon Receptor anticorps

Épitope: AA 12-215

Fonction: AHR antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 12-215aa

Immunogen: aryl hydrocarbon receptor

Isotype: IgG

Information d'application

Indications d'application: WB: 1:200-1:2000, IP: 1:200-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur Aryl Hydrocarbon Receptor

Antigène: Aryl Hydrocarbon Receptor (AHR)

Autre désignation: AHR

Sujet:

Synonyms: Aryl hydrocarbon receptor (Ah receptor, AhR)|Class E basic helix-loop-helix protein 76 (bHLHe76)|AHR|BHLHE76

Background: Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes(such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.

Poids moléculaire: 105 kDa

ID gène: 196

UniProt: P35869

Pathways: Regulation of Cell Size