Asialoglycoprotein Receptor 1 anticorps

N° du produit ABIN7111748

L’anticorps Lapin Polyclonal anti-Asialoglycoprotein Receptor 1 a été validé pour WB, ELISA et IHC. Il convient pour détecter Asialoglycoprotein Receptor 1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Asialoglycoprotein Receptor 1 anticorps (ABIN7111748)

Antigène: Asialoglycoprotein Receptor 1 (ASGR1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Asialoglycoprotein Receptor 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-Asialoglycoprotein Receptor 1 anticorps

Fonction: ASGR1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 145-252

Immunogen: asialoglycoprotein receptor 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:1000 - 1:4000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur Asialoglycoprotein Receptor 1

Antigène: Asialoglycoprotein Receptor 1 (ASGR1)

Autre désignation: ASGR1

Sujet:

Synonyms: Asialoglycoprotein receptor 1 (ASGP-R 1, ASGPR 1)|C-type lectin domain family 4 member H1|Hepatic lectin H1 (HL-1)|ASGR1|CLEC4H1

Background: This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Poids moléculaire: 40 kDa

ID gène: 432

UniProt: P07306

Pathways: Thyroid Hormone Synthesis