ABCC6 anticorps

N° du produit ABIN7111820

L’anticorps anti-ABCC6 Polyclonal Lapin est utilisé pour la détection de ABCC6 dans des échantillons de Humain. Il a été validé pour IHC et ELISA.

Aperçu rapide pour ABCC6 anticorps (ABIN7111820)

Antigène: ABCC6 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 6 (ABCC6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABCC6 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-ABCC6 anticorps

Fonction: ABCC6 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 1437-1499

Immunogen: ATP-binding cassette, sub-family C (CFTR/MRP), member 6

Isotype: IgG

Information d'application

Indications d'application: IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur ABCC6

Antigène: ABCC6 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 6 (ABCC6))

Autre désignation: ABCC6

Sujet:

Synonyms: ATP-binding cassette sub-family C member 6|Anthracycline resistance-associated protein|Multi-specific organic anion transporter E (MOAT-E)|Multidrug resistance-associated protein 6|ABCC6|ARA|MRP6

Background: The ATP-binding cassette transporter 6 (ABCC6) gene, also named as MRP6, is a cellular transmembrane protein transporter and belongs to ATP-binding cassette (ABC) family. ABCC6 is an ATP-dependent transporter contains two ATP-binding domains. It is mainly found in the liver, the proximal tubules of the kidneys and the intestines. ABCC6 is involved in a pathway of extracellular nucleotide metabolism and the regulation of tissue calcification. Mutations of ABCC6 leads to pseudoxanthoma elasticum (PXE) which is a rare autosomal recessive disorder. Mutations of ABCC6 can also lead generalized arterial calcification of infancy-2 (GACI2).

Poids moléculaire: 165 kDa

UniProt: O95255