BCOR anticorps

N° du produit ABIN7111972

Cet anticorps Lapin Polyclonal détecte spécifiquement BCOR dans WB et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour BCOR anticorps (ABIN7111972)

Antigène: BCOR (BCL6 Co-Repressor (BCOR))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCOR est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-BCOR anticorps

Fonction: BCOR antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: BCL6 co-repressor

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur BCOR

Antigène: BCOR (BCL6 Co-Repressor (BCOR))

Autre désignation: BCOR

Sujet:

Synonyms: BCL-6 corepressor (BCoR)|BCOR|KIAA1575

Background: Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A, impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells, the function implies inhibition of methylation on histone H3 'Lys-4'(H3K4me3) and 'Lys-36'(H3K36me2).

Poids moléculaire: 186 kDa

ID gène: 54880

UniProt: Q6W2J9