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CASQ2 anticorps

Cet anticorps Lapin Polyclonal détecte spécifiquement CASQ2 dans WB, ELISA et IHC. Il présente une réactivité envers Humain, Souris et Rat.
N° du produit ABIN7112233

Aperçu rapide pour CASQ2 anticorps (ABIN7112233)

Antigène

Voir toutes CASQ2 Anticorps
CASQ2 (Calsequestrin 2 (CASQ2))

Reactivité

  • 32
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 29
  • 6
Lapin

Clonalité

  • 30
  • 5
Polyclonal

Conjugué

  • 20
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp CASQ2 est non-conjugé

Application

  • 24
  • 16
  • 7
  • 3
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • Fonction

    CASQ2 antibody

    Purification

    Immunogen affinity purified

    Pureté

    ≥95 % as determined by SDS-PAGE

    Immunogène

    calsequestrin 2(cardiac muscle)

    Isotype

    IgG
  • Indications d'application

    WB: 1:500-1:2000, IHC: 1:20-1:200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze / thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    -20°C for 12 months

    Date de péremption

    12 months
  • Antigène

    CASQ2 (Calsequestrin 2 (CASQ2))

    Autre désignation

    CASQ2

    Sujet

    Synonyms: Calsequestrin-2|Calsequestrin, cardiac muscle isoform|CASQ2

    Background: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, especially at the interface between subunits. Can bind around 60 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR2, this plays an important role in triggering muscle contraction. Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats.

    Poids moléculaire

    55 kDa

    UniProt

    O14958

    Pathways

    Negative Regulation of Transporter Activity
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