CASQ2 anticorps
Aperçu rapide pour CASQ2 anticorps (ABIN7112233)
Antigène
Voir toutes CASQ2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- CASQ2 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- calsequestrin 2(cardiac muscle)
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000, IHC: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- CASQ2 (Calsequestrin 2 (CASQ2))
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Autre désignation
- CASQ2
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Sujet
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Synonyms: Calsequestrin-2|Calsequestrin, cardiac muscle isoform|CASQ2
Background: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, especially at the interface between subunits. Can bind around 60 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR2, this plays an important role in triggering muscle contraction. Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats.
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Poids moléculaire
- 55 kDa
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UniProt
- O14958
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Pathways
- Negative Regulation of Transporter Activity
Antigène
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