CHST14 anticorps

N° du produit ABIN7112278

Cet anticorps Lapin Polyclonal détecte spécifiquement CHST14 dans WB, ELISA et IHC. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour CHST14 anticorps (ABIN7112278)

Antigène: CHST14 (Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 (CHST14))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHST14 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-CHST14 anticorps

Fonction: CHST14 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: carbohydrate(N-acetylgalactosamine 4-0) sulfotransferase 14

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur CHST14

Antigène: CHST14 (Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 (CHST14))

Autre désignation: CHST14

Sujet:

Synonyms: Carbohydrate sulfotransferase 14|Dermatan 4-sulfotransferase 1 (D4ST-1, hD4ST1)|CHST14|D4ST1

Background: Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine(GalNAc) residue of dermatan sulfate. Plays a pivotal role in the formation of 4-0-sulfated IdoA blocks in dermatan sulfate. Transfers sulfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid(IdoUA) at the C-3 hydroxyl. Transfers sulfate more efficiently to GalNAc residues in-IdoUA-GalNAc-IdoUA-than in-GlcUA-GalNAc-GlcUA-sequences. Has preference for partially desulfated dermatan sulfate. Addition of sulfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA. GlcUA to IdoUA. Appears to have an important role in the formation of the cerbellar neural network during postnatal brain development.

Poids moléculaire: 45-50 kDa

ID gène: 113189

UniProt: Q8NCH0

Pathways: Glycosaminoglycan Metabolic Process