CTCFL anticorps (AA 361-663)

N° du produit ABIN7112427

Cet anticorps anti-CTCFL est un anticorps Souris Monoclonal détectant CTCFL dans WB, ELISA et IF. Adapté pour Humain et Souris.

Aperçu rapide pour CTCFL anticorps (AA 361-663) (ABIN7112427)

Antigène: CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CTCFL est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 2B10

Détail du produit anti-CTCFL anticorps

Épitope: AA 361-663

Fonction: CTCFL antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 361-663aa

Immunogen: CCCTC-binding factor(zinc finger protein)-like

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:500-1:2000, IF: 1:10-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur CTCFL

Antigène: CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))

Autre désignation: CTCFL

Sujet:

Synonyms: Transcriptional repressor CTCFL|Brother of the regulator of imprinted sites|CCCTC-binding factor|CTCF paralog|CTCF-like protein|Cancer/testis antigen 27 (CT27)|Zinc finger protein CTCF-T|CTCFL|BORIS

Background: CTCFL, also named BORIS(for brother of the regulator of imprinted sites) is a paralogue of the 11 zinc-finger transcription factor, CTCF. It is predominantly expressed in spermatocytes in the testis, also can be found in tumors and cancer cell lines. It mainly participates in insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers. It has a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region(ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 'Arg-3' to form H4R3sme2.

Poids moléculaire: 75 kDa

ID gène: 140690

UniProt: Q8NI51