CNOT3 anticorps

N° du produit ABIN7112435

L’anticorps Lapin Polyclonal anti-CNOT3 a été validé pour WB, ELISA, IF et IP. Il convient pour détecter CNOT3 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CNOT3 anticorps (ABIN7112435)

Antigène: CNOT3 (CCR4-NOT Transcription Complex, Subunit 3 (CNOT3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CNOT3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Détail du produit anti-CNOT3 anticorps

Fonction: CNOT3 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: CCR4-NOT transcription complex, subunit 3

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:1000, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur CNOT3

Antigène: CNOT3 (CCR4-NOT Transcription Complex, Subunit 3 (CNOT3))

Autre désignation: CNOT3

Sujet:

Synonyms: CCR4-NOT transcription complex subunit 3|CCR4-associated factor 3|Leukocyte receptor cluster member 2|CNOT3|KIAA0691|LENG2|NOT3

Background: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in metabolic regulation, may be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism. Involved in mitotic progression and regulation of the spindle assembly checkpoint by regulating the stability of MAD1L1 mRNA. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation, the repressive function may involve histone deacetylases. Involved in the maintenance of emryonic stem(ES) cell identity.

Poids moléculaire: 120 kDa

ID gène: 4849

UniProt: O75175

Pathways: Stem Cell Maintenance