CNOT7 anticorps

N° du produit ABIN7112436

Cet anticorps anti-CNOT7 est un anticorps Lapin Polyclonal détectant CNOT7 dans WB, ELISA et IP. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour CNOT7 anticorps (ABIN7112436)

Antigène: CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CNOT7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Détail du produit anti-CNOT7 anticorps

Fonction: CNOT7 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: CCR4-NOT transcription complex, subunit 7

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur CNOT7

Antigène: CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

Autre désignation: CNOT7

Sujet:

Synonyms: CCR4-NOT transcription complex subunit 7|BTG1-binding factor 1|CCR4-associated factor 1 (CAF-1)|Caf1a|CNOT7|CAF1

Background: Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.

Poids moléculaire: 33-35 kDa

ID gène: 29883

UniProt: Q9UIV1

Pathways: Ribonucleoprotein Complex Subunit Organization