CDC14B anticorps

N° du produit ABIN7112534

L’anticorps Lapin Polyclonal anti-CDC14B a été validé pour WB et ELISA. Il convient pour détecter CDC14B dans des échantillons de Humain.

Aperçu rapide pour CDC14B anticorps (ABIN7112534)

Antigène: CDC14B (CDC14 Cell Division Cycle 14B (CDC14B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDC14B est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CDC14B anticorps

Fonction: CDC14B antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: CDC14 cell division cycle 14 homolog B

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur CDC14B

Antigène: CDC14B (CDC14 Cell Division Cycle 14B (CDC14B))

Autre désignation: CDC14B

Sujet:

Synonyms: Dual specificity protein phosphatase CDC14B|CDC14 cell division cycle 14 homolog B|CDC14B

Background: Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damage checkpoint: following DNA damage, translocates to the nucleus and dephosphorylates FZR1/CDH1, a key activator of the anaphase promoting complex/cyclosome(APC/C). Dephosphorylates SIRT2 around early anaphase. Dephosphorylation of FZR1/CDH1 activates the APC/C, leading to the ubiquitination of PLK1, preventing entry into mitosis. Preferentially dephosphorylates proteins modified by proline-directed kinases.

Poids moléculaire: 56 kDa

ID gène: 8555

UniProt: O60729