CDC14B anticorps

N° du produit ABIN7112534

Détail du produit anti-CDC14B anticorps

Antigène: CDC14B (CDC14 Cell Division Cycle 14B (CDC14B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDC14B est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: CDC14 cell division cycle 14 homolog B(S. cerevisiae)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur CDC14B

Antigène: CDC14B (CDC14 Cell Division Cycle 14B (CDC14B))

Autre désignation: CDC14B (CDC14B Produits)

Synonymes: anticorps CDC14B, anticorps 2810432N10Rik, anticorps A530086E13Rik, anticorps AA472821, anticorps CDC14B3, anticorps Cdc14B1, anticorps Cdc14B2, anticorps hCDC14B, anticorps Dual specificity protein phosphatase CDC14B, anticorps dual specificity protein phosphatase CDC14B, anticorps cell division cycle 14B, anticorps CDC14 cell division cycle 14B, anticorps Bm1_19115, anticorps LOAG_10083, anticorps CDC14B, anticorps cdc14b, anticorps Cdc14b

Sujet: Synonyms: Background:Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damage checkpoint: following DNA damage, translocates to the nucleus and dephosphorylates FZR1/CDH1, a key activator of the anaphase promoting complex/cyclosome(APC/C). Dephosphorylates SIRT2 around early anaphase. Dephosphorylation of FZR1/CDH1 activates the APC/C, leading to the ubiquitination of PLK1, preventing entry into mitosis. Preferentially dephosphorylates proteins modified by proline-directed kinases.

Poids moléculaire: 56 kDa

ID gène: 8555

UniProt: O60729