CIDEA anticorps

N° du produit ABIN7112559

Cet anticorps anti-CIDEA est un anticorps Lapin Polyclonal détectant CIDEA dans WB et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour CIDEA anticorps (ABIN7112559)

Antigène: CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CIDEA est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CIDEA anticorps

Fonction: CIDEA antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: cell death-inducing DFFA-like effector a

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur CIDEA

Antigène: CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Autre désignation: CIDEA

Sujet:

Synonyms: Lipid transferase CIDEA|Cell death activator CIDE-A|Cell death-inducing DFFA-like effector A|CIDEA

Background: Acts as a CEBPB coactivator in mammary epithelial cells to control the expression of a subset of CEBPB downstream target genes, including ID2, IGF1, PRLR, SOCS1, SOCS3, XDH, but not casein. By interacting with CEBPB, strengthens the association of CEBPB with the XDH promoter, increases histone acetylation and dissociates HDAC1 from the promoter(By similarity). Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair and occurs at a lower rate than that promoted by CIDEC. When overexpressed, induces apoptosis. The physiological significance of its role in apoptosis is unclear.

Poids moléculaire: 25 kDa

ID gène: 1149

UniProt: O60543