CEP290 anticorps

N° du produit ABIN7112607

Cet anticorps anti-CEP290 est un anticorps Lapin Polyclonal détectant CEP290 dans ELISA, WB, IHC, IF et IP. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour CEP290 anticorps (ABIN7112607)

Antigène: CEP290 (Centrosomal Protein 290kDa (CEP290))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CEP290 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Détail du produit anti-CEP290 anticorps

Fonction: CEP290 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: centrosomal protein 290kDa

Isotype: IgG

Information d'application

Indications d'application: WB: 1:200-1:2000, IP: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:50-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur CEP290

Antigène: CEP290 (Centrosomal Protein 290kDa (CEP290))

Autre désignation: CEP290

Sujet:

Synonyms: Centrosomal protein of 290 kDa (Cep290)|Bardet-Biedl syndrome 14 protein|Cancer/testis antigen 87 (CT87)|Nephrocystin-6|Tumor antigen se2-2|CEP290|BBS14|KIAA0373|NPHP6

Background: Studies in the Chlamydomonas model system has shown that the ciliary protein CEP290 is a critical component of these Y-link junctions. Additionally, numerous studies have demonstrated that CEP290's function is critical for IFT-in CEP290 knockdown experiments, many proteins that would normally localize to the cilium fail to do so, and cilium formation is disrupted or absent. Mutations in CEP290 are accountable for cases of nephronophthisis, Leber congenital amaurosis and Joubert syndrome. In IF analtsis of HeLa cells, the white arrows show centrosome and cilium staining.

Poids moléculaire: 290 kDa, 150-180 kDa, 80 kDa, 60 kDa

ID gène: 80184

UniProt: O15078

Pathways: cAMP Metabolic Process, M Phase