CEP290 anticorps

N° du produit ABIN7112607

Détail du produit anti-CEP290 anticorps

Antigène: CEP290 (Centrosomal Protein 290kDa (CEP290))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CEP290 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: centrosomal protein 290kDa

Isotype: IgG

Information d'application

Indications d'application: WB: 1:200-1:2000, IP: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:50-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur CEP290

Antigène: CEP290 (Centrosomal Protein 290kDa (CEP290))

Autre désignation: CEP290 (CEP290 Produits)

Synonymes: anticorps ct87, anticorps mks4, anticorps rd16, anticorps bbs14, anticorps jbts5, anticorps jbts6, anticorps lca10, anticorps nphp6, anticorps slsn6, anticorps sh11ag, anticorps MGC81471, anticorps 3h11ag, anticorps RGD1311640, anticorps BC004690, anticorps Nphp6, anticorps b2b1454Clo, anticorps b2b1752Clo, anticorps im:7145703, anticorps im:7147820, anticorps 3H11Ag, anticorps BBS14, anticorps CT87, anticorps JBTS5, anticorps LCA10, anticorps MKS4, anticorps NPHP6, anticorps POC3, anticorps SLSN6, anticorps centrosomal protein 290, anticorps centrosomal protein 290 L homeolog, anticorps centrosomal protein 290kDa, anticorps CEP290, anticorps cep290.L, anticorps cep290, anticorps Cep290

Sujet: Synonyms:BBS14, KIAA0373, NPHP6,LCA10, MKS4, Nephrocystin 6, rd16, SLSN6, Tumor antigen se2 2 Background:Studies in the Chlamydomonas model system has shown that the ciliary protein CEP290 is a critical component of these Y-link junctions. Additionally, numerous studies have demonstrated that CEP290's function is critical for IFT-in CEP290 knockdown experiments, many proteins that would normally localize to the cilium fail to do so, and cilium formation is disrupted or absent. Mutations in CEP290 are accountable for cases of nephronophthisis, Leber congenital amaurosis and Joubert syndrome. In IF analtsis of HeLa cells, the white arrows show centrosome and cilium staining.

Poids moléculaire: 290 kDa, 150-180 kDa, 80 kDa, 60 kDa

ID gène: 80184

UniProt: O15078

Pathways: cAMP Metabolic Process, M Phase