CHMP4B anticorps

N° du produit ABIN7112648

L’anticorps Lapin Polyclonal anti-CHMP4B a été validé pour IHC, ELISA et WB. Il convient pour détecter CHMP4B dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CHMP4B anticorps (ABIN7112648)

Antigène: CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHMP4B est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Western Blotting (WB)

Détail du produit anti-CHMP4B anticorps

Fonction: CHMP4B antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: chromatin modifying protein 4B

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur CHMP4B

Antigène: CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))

Autre désignation: CHMP4B

Sujet:

Synonyms: Charged multivesicular body protein 4b|Chromatin-modifying protein 4b (CHMP4b)|SNF7 homolog associated with Alix 1|SNF7-2 (hSnf7-2)|Vacuolar protein sorting-associated protein 32-2 (Vps32-2, hVps32-2)|CHMP4B|C20orf178|SHAX1

Background: This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies. Mutations in this gene result in autosomal dominant posterior polar cataracts.

Poids moléculaire: 35 kDa

ID gène: 128866

UniProt: Q9H444