CHMP6 anticorps

N° du produit ABIN7112649

Cet anticorps anti-CHMP6 est un anticorps Lapin Polyclonal détectant CHMP6 dans WB et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour CHMP6 anticorps (ABIN7112649)

Antigène: CHMP6 (Charged Multivesicular Body Protein 6 (CHMP6))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHMP6 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CHMP6 anticorps

Fonction: CHMP6 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: chromatin modifying protein 6

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur CHMP6

Antigène: CHMP6 (Charged Multivesicular Body Protein 6 (CHMP6))

Autre désignation: CHMP6

Sujet:

Synonyms: Charged multivesicular body protein 6|Chromatin-modifying protein 6|Vacuolar protein sorting-associated protein 20 (Vps20, hVps20)|CHMP6|VPS20

Background: Probable core component of the endosomal sorting required for transport complex III(ESCRT-III) which is involved in multivesicular bodies(MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles(ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O,-I,-II and-III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses(HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. In the ESCRT-III complex, it probably serves as an acceptor for the ESCRT-II complex on endosomal membranes.

Poids moléculaire: 28-30 kDa

ID gène: 79643

UniProt: Q96FZ7