CHRNA9 anticorps
Aperçu rapide pour CHRNA9 anticorps (ABIN7112723)
Antigène
Voir toutes CHRNA9 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- CHRNA9 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- cholinergic receptor, nicotinic, alpha 9
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- CHRNA9 (Cholinergic Receptor, Nicotinic, alpha 9 (Neuronal) (CHRNA9))
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Autre désignation
- CHRNA9
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Sujet
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Synonyms: Neuronal acetylcholine receptor subunit alpha-9|Nicotinic acetylcholine receptor subunit alpha-9 (NACHR alpha-9)|CHRNA9|NACHRA9
Background: Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding induces a conformation change that leads to the opening of an ion-conducting channel across the plasma membrane(PubMed:11752216, PubMed:25282151). The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane(PubMed:11752216, PubMed:25282151). In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. May also regulate keratinocyte adhesion(PubMed:11021840).
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Poids moléculaire
- 50-55 kDa
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ID gène
- 55584
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UniProt
- Q9UGM1
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Pathways
- Sensory Perception of Sound
Antigène
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