CNDP2 anticorps

N° du produit ABIN7112896

Cet anticorps Lapin Polyclonal détecte spécifiquement CNDP2 dans WB, ELISA et IF. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour CNDP2 anticorps (ABIN7112896)

Antigène: CNDP2 (CNDP Dipeptidase 2 (Metallopeptidase M20 Family) (CNDP2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CNDP2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-CNDP2 anticorps

Fonction: CNDP2 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: CNDP dipeptidase 2(metallopeptidase M20 family)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur CNDP2

Antigène: CNDP2 (CNDP Dipeptidase 2 (Metallopeptidase M20 Family) (CNDP2))

Autre désignation: CNDP2

Sujet:

Synonyms: Cytosolic non-specific dipeptidase|CNDP dipeptidase 2|Glutamate carboxypeptidase-like protein 1|Peptidase A|Threonyl dipeptidase|CNDP2|CN2|CPGL|HEL-S-13|PEPA

Background: Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly(PubMed:19346245). Acts as a functional tumor suppressor in gastric cancer via activation of the mitogen-activated protein kinase(MAPK) pathway. An elevated level of CNDP2 activates the p38 and JNK MAPK pathways to induce cell apoptosis, and a lower level of CNDP2 activates the ERK MAPK pathway to promote cell proliferation(PubMed:24395568). Isoform 2 may play a role as tumor suppressor in hepatocellular carcinoma(HCC) cells(PubMed:17121880). Catalyzes the production of N-lactoyl-amino acids from lactate and amino acids by reverse proteolysis(PubMed:25964343).

Poids moléculaire: 54 kDa

ID gène: 55748

UniProt: Q96KP4