CC2D1A anticorps

N° du produit ABIN7112928

Cet anticorps anti-CC2D1A est un anticorps Lapin Polyclonal détectant CC2D1A dans WB, IHC, ELISA et IF. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour CC2D1A anticorps (ABIN7112928)

Antigène: CC2D1A (Coiled-Coil and C2 Domain Containing 1A (CC2D1A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CC2D1A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-CC2D1A anticorps

Fonction: CC2D1A antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: coiled-coil and C2 domain containing 1A

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur CC2D1A

Antigène: CC2D1A (Coiled-Coil and C2 Domain Containing 1A (CC2D1A))

Autre désignation: CC2D1A

Sujet:

Synonyms: Coiled-coil and C2 domain-containing protein 1A|Akt kinase-interacting protein 1|Five prime repressor element under dual repression-binding protein 1 (FRE under dual repression-binding protein 1, Freud-1)|Putative NF-kappa-B-activating protein 023N|CC2D1A|AKI1

Background: Transcription factor that binds specifically to the DRE(dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses(By similarity). Plays distinct roles depending on its localization. When cytoplasmic, acts as a scaffold protein in the PI3K/PDK1/AKT pathway. Repressor of HTR1A when nuclear. In the centrosome, regulates spindle pole localization of the cohesin subunit SCC1/RAD21, thereby mediating centriole cohesion during mitosis.

Poids moléculaire: 130 kDa, 104 kDa

ID gène: 54862

UniProt: Q6P1N0