Collagen Type I anticorps
Aperçu rapide pour Collagen Type I anticorps (ABIN7112980)
Antigène
Voir toutes Collagen Type I (COL1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Fonction
- Collagen Type I antibody
-
Purification
- protein A+G purified
-
Pureté
- ≥95 % as determined by SDS-PAGE
-
Immunogène
- collagen, type I, alpha 2
-
Isotype
- IgG1
-
-
-
-
Indications d'application
- IHC: 1:200 - 1:1000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- -20°C for 12 months
-
Date de péremption
- 12 months
-
-
- Collagen Type I (COL1) (Collagen, Type I (COL1))
-
Autre désignation
- Collagen Type I
-
Sujet
-
Synonyms: Collagen alpha-2(I) chain|Alpha-2 type I collagen|COL1A2
Background: This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
-
ID gène
- 1278
-
UniProt
- P08123
Antigène
-