Cyclin Y anticorps
Aperçu rapide pour Cyclin Y anticorps (ABIN7113157)
Antigène
Voir toutes Cyclin Y (CCNY) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- CCNY antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- cyclin Y
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000, IP: 1:500-1:1000, IF: 1:10-1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- Cyclin Y (CCNY)
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Autre désignation
- CCNY
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Sujet
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Synonyms: Cyclin-Y (Cyc-Y)|Cyclin box protein 1|Cyclin fold protein 1|cyclin-X|CCNY|C10orf9|CBCP1|CFP1
Background: Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription.
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Poids moléculaire
- 33-39 kDa
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ID gène
- 219771
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UniProt
- Q8ND76
Antigène
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