DACH2 anticorps

N° du produit ABIN7113311

L’anticorps Lapin Polyclonal anti-DACH2 a été validé pour WB et ELISA. Il convient pour détecter DACH2 dans des échantillons de Humain et Souris.

Aperçu rapide pour DACH2 anticorps (ABIN7113311)

Antigène: DACH2 (Dachshund 2 (DACH2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DACH2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-DACH2 anticorps

Fonction: DACH2 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: dachshund homolog 2(Drosophila)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur DACH2

Antigène: DACH2 (Dachshund 2 (DACH2))

Autre désignation: DACH2

Sujet:

Synonyms: Dachshund homolog 2 (Dach2)|DACH2

Background: Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator for SIX1 and SIX6. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter. Is recruited with SIX6 to the p27Kip1 promoter in embryonal retina. SIX6 corepression seems also to involve NCOR1, TBL1, HDAC1 and HDAC3. May be involved together with PAX3, SIX1, and EYA2 in regulation of myogenesis. In the developing somite, expression of DACH2 and PAX3 is regulated by the overlying ectoderm, and DACH2 and PAX3 positively regulate each other's expression(By similarity). Probably binds to DNA via its DACHbox-N domain.

Poids moléculaire: 65 kDa

ID gène: 117154

UniProt: Q96NX9