DOCK7 anticorps

N° du produit ABIN7113381

Cet anticorps anti-DOCK7 est un anticorps Lapin Polyclonal détectant DOCK7 dans ELISA, WB et IP. Adapté pour Humain, Rat et Souris.

Aperçu rapide pour DOCK7 anticorps (ABIN7113381)

Antigène: DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOCK7 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-DOCK7 anticorps

Fonction: DOCK7 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: dedicator of cytokinesis 7

Isotype: IgG

Information d'application

Indications d'application: WB: 1:200-1:1000, IP: 1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur DOCK7

Antigène: DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))

Autre désignation: DOCK7

Sujet:

Synonyms: Dedicator of cytokinesis protein 7|DOCK7|KIAA1771

Background: Functions as a guanine nucleotide exchange factor(GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization(PubMed:16982419). Has a role in pigmentation(By similarity). Involved in the regulation of cortical neurogenesis through the control of radial glial cells(RGCs) proliferation versus differentiation, negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3(By similarity).Multiple isoforms of DOCK 7 exist due to alternative splicing events. This DOCK 7 antibody can recognize all the isoforms.

Poids moléculaire: 240 kDa

ID gène: 85440

UniProt: Q96N67