DOCK7 anticorps

N° du produit ABIN7113381

Détail du produit anti-DOCK7 anticorps

Antigène: DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOCK7 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: dedicator of cytokinesis 7

Isotype: IgG

Information d'application

Indications d'application: WB: 1:200-1:1000, IP: 1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur DOCK7

Antigène: DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))

Autre désignation: DOCK7 (DOCK7 Produits)

Synonymes: anticorps im:7145816, anticorps im:7157388, anticorps wu:fb93h07, anticorps ZIR2, anticorps 3110056M06Rik, anticorps Gm430, anticorps m, anticorps mKIAA1771, anticorps dedicator of cytokinesis 7, anticorps dedicator of cytokinesis protein 7, anticorps dedicator of cytokinesis 6, anticorps DOCK7, anticorps dock7, anticorps NAEGRDRAFT_56982, anticorps LOC100185115, anticorps dock6, anticorps Dock7

Sujet: Synonyms:dedicator of cytokinesis 7, DOCK7, KIAA1771, ZIR2 Background:Functions as a guanine nucleotide exchange factor(GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization(PubMed:16982419). Has a role in pigmentation(By similarity). Involved in the regulation of cortical neurogenesis through the control of radial glial cells(RGCs) proliferation versus differentiation, negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3(By similarity).Multiple isoforms of DOCK 7 exist due to alternative splicing events. This DOCK 7 antibody can recognize all the isoforms.

Poids moléculaire: 240 kDa

ID gène: 85440

UniProt: Q96N67