DCUN1D1 anticorps

N° du produit ABIN7113384

Détail du produit anti-DCUN1D1 anticorps

Antigène: DCUN1D1 (Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DCUN1D1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: DCN1, defective in cullin neddylation 1, domain containing 1(S. cerevisiae)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur DCUN1D1

Antigène: DCUN1D1 (Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1))

Autre désignation: DCUN1D1 (DCUN1D1 Produits)

Synonymes: anticorps fd19a01, anticorps zgc:66414, anticorps wu:fd19a01, anticorps dcun1l1, anticorps rp42, anticorps sccro, anticorps scro, anticorps tes3, anticorps DCNL1, anticorps DCUN1L1, anticorps RP42, anticorps SCCRO, anticorps SCRO, anticorps Tes3, anticorps Rp42, anticorps pTes3, anticorps DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae), anticorps DCN1-like protein 1, anticorps DCN1, defective in cullin neddylation 1, domain containing 1 L homeolog, anticorps defective in cullin neddylation 1 domain containing 1, anticorps dcun1d1, anticorps dcnl1, anticorps dcun1d1.L, anticorps DCUN1D1, anticorps Dcun1d1

Sujet: Synonyms:DCUN1L1, RP42, SCCRO Background:Part of an E3 ubiquitin ligase complex for neddylation. Promotes neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes. Acts by binding to cullin-RBX1 complexes in the cytoplasm and promoting their nuclear translocation, enhancing recruitment of E2-NEDD8(UBE2M-NEDD8) thioester to the complex, and optimizing the orientation of proteins in the complex to allow efficient transfer of NEDD8 from the E2 to the cullin substrates(PubMed:25349211). Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression(By similarity).

Poids moléculaire: 28 kDa

ID gène: 54165

UniProt: Q96GG9