Desmoglein 1 anticorps

N° du produit ABIN7113447

Cet anticorps anti-Desmoglein 1 est un anticorps Lapin Polyclonal détectant Desmoglein 1 dans WB, IHC, IF et ELISA. Adapté pour Humain et Rat.

Aperçu rapide pour Desmoglein 1 anticorps (ABIN7113447)

Antigène: Desmoglein 1 (DSG1)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Desmoglein 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Détail du produit anti-Desmoglein 1 anticorps

Fonction: DSG1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: Desmoglein-1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:50-1:200, IF: 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur Desmoglein 1

Antigène: Desmoglein 1 (DSG1)

Autre désignation: DSG1

Sujet:

Synonyms: Desmoglein-1|Cadherin family member 4|Desmosomal glycoprotein 1 (DG1, DGI)|Pemphigus foliaceus antigen|DSG1|CDHF4

Background: This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.

Poids moléculaire: 150 kDa

ID gène: 1828

UniProt: Q02413

Pathways: Cell-Cell Junction Organization