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DNMT3A anticorps

DNMT3A Reactivité: Humain, Souris, Rat WB, ELISA, IP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7113542
  • Antigène Voir toutes DNMT3A Anticorps
    DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
    Reactivité
    • 122
    • 48
    • 47
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 114
    • 10
    Lapin
    Clonalité
    • 106
    • 18
    Polyclonal
    Conjugué
    • 51
    • 11
    • 10
    • 10
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DNMT3A est non-conjugé
    Application
    • 94
    • 59
    • 30
    • 27
    • 26
    • 16
    • 10
    • 8
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    Purification
    Immunogen affinity purified
    Pureté
    ≥95 % as determined by SDS-PAGE
    Immunogène
    DNA(cytosine-5-)-methyltransferase 3 alpha
    Isotype
    IgG
    Top Product
    Discover our top product DNMT3A Anticorps primaire
  • Indications d'application
    WB: 1:500-1:2000, IP: 1:200-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Date de péremption
    12 months
  • Antigène
    DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
    Autre désignation
    DNMT3A (DNMT3A Produits)
    Synonymes
    anticorps DNMT3A, anticorps DNMT3A2, anticorps M.HsaIIIA, anticorps MmuIIIA, anticorps dnmt3a1, anticorps dnmt6, anticorps DNA methyltransferase 3 alpha, anticorps DNA methyltransferase 3A, anticorps DNA (cytosine-5-)-methyltransferase 3 alpha b, anticorps DNMT3A, anticorps Dnmt3a, anticorps dnmt3a, anticorps dnmt3ab
    Sujet
    Synonyms: Background:Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZBTB18. Recruited to trimethylated 'Lys-36' of histone H3(H3K36me3) sites. Can actively repress transcription through the recruitment of HDAC activity.
    ID gène
    1788
    UniProt
    Q9Y6K1
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