DOC2B anticorps
Aperçu rapide pour DOC2B anticorps (ABIN7113615)
Antigène
Voir toutes DOC2B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- DOC2B antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- double C2-like domains, beta
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000, IF: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- DOC2B (Double C2-Like Domains, beta (DOC2B))
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Autre désignation
- DOC2B
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Sujet
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Synonyms: Double C2-like domain-containing protein beta (Doc2-beta)|DOC2B|DOC2BL
Background: Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes. Binds phospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma membrane in adipocytes(By similarity).
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Poids moléculaire
- 46 kDa
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ID gène
- 8447
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UniProt
- Q14184
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Pathways
- Positive Regulation of Peptide Hormone Secretion
Antigène
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