EHD1 anticorps

N° du produit ABIN7113753

Cet anticorps anti-EHD1 est un anticorps Lapin Polyclonal détectant EHD1 dans WB, ELISA et IF. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour EHD1 anticorps (ABIN7113753)

Antigène: EHD1 (EH-Domain Containing 1 (EHD1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EHD1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-EHD1 anticorps

Fonction: EHD1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: EH-domain containing 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur EHD1

Antigène: EHD1 (EH-Domain Containing 1 (EHD1))

Autre désignation: EHD1

Sujet:

Synonyms: EH domain-containing protein 1|PAST homolog 1 (hPAST1)|Testilin|EHD1|PAST|PAST1

Background: ATP-and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes vesiculation of endocytic membranes(PubMed:24019528). Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes(PubMed:15020713, PubMed:17233914, PubMed:20801876). Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth(By similarity). Plays a role in myoblast fusion(By similarity). Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing(By similarity). Plays a role in the formation of the ciliary vesicle(CV), an early step in cilium biogenesis. Proposed to be required for the fusion of distal appendage vesicles(DAVs) to form the CV by recruiting SNARE complex component SNAP29. Is required for recruitment of transition zone proteins CEP290, RPGRIP1L, TMEM67 and B9D2, and of IFT20 following DAV reorganization before Rab8-dependent ciliary membrane extension. Required for the loss of CCP110 form the mother centriole essential for the maturation of the basal body during ciliogenesis(PubMed:25686250).

Poids moléculaire: 61 kDa

ID gène: 10938

UniProt: Q9H4M9

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development