ELK4 anticorps

N° du produit ABIN7113769

Cet anticorps Lapin Polyclonal détecte spécifiquement ELK4 dans WB et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour ELK4 anticorps (ABIN7113769)

Antigène: ELK4 (ELK4, ETS-Domain Protein (SRF Accessory Protein 1) (ELK4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ELK4 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ELK4 anticorps

Fonction: ELK4 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: ELK4, ETS-domain protein(SRF accessory protein 1)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur ELK4

Antigène: ELK4 (ELK4, ETS-Domain Protein (SRF Accessory Protein 1) (ELK4))

Autre désignation: ELK4

Sujet:

Synonyms: ETS domain-containing protein Elk-4|Serum response factor accessory protein 1 (SAP-1, SRF accessory protein 1)|ELK4|SAP1

Background: Involved in both transcriptional activation and repression. Interaction with SIRT7 leads to recruitment and stabilization of SIRT7 at promoters, followed by deacetylation of histone H3 at 'Lys-18'(H3K18Ac) and subsequent transcription repression. Forms a ternary complex with the serum response factor(SRF). Requires DNA-bound SRF for ternary complex formation and makes extensive DNA contacts to the 5'side of SRF, but does not bind DNA autonomously.

Poids moléculaire: 47 kDa

ID gène: 2005

UniProt: P28324