ELL anticorps

N° du produit ABIN7113778

Cet anticorps Lapin Polyclonal détecte spécifiquement ELL dans WB, ELISA et IHC. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour ELL anticorps (ABIN7113778)

Antigène: ELL (Elongation Factor RNA Polymerase II (ELL))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ELL est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-ELL anticorps

Fonction: ELL antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: elongation factor RNA polymerase II

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur ELL

Antigène: ELL (Elongation Factor RNA Polymerase II (ELL))

Autre désignation: ELL

Sujet:

Synonyms: RNA polymerase II elongation factor ELL|Eleven-nineteen lysine-rich leukemia protein|ELL|C19orf17

Background: Elongation factor component of the super elongation complex(SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Elongation factor component of the little elongation complex(LEC), a complex required to regulate small nuclear RNA(snRNA) gene transcription by RNA polymerase II and III(PubMed:22195968, PubMed:23932780). Specifically required for stimulating the elongation step of RNA polymerase II-and III-dependent snRNA gene transcription(PubMed:23932780). ELL also plays an early role before its assembly into in the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site. Required to stabilize the pre-initiation complex and early elongation.

Poids moléculaire: 68-80 kDa

ID gène: 8178

UniProt: P55199