ELL2 anticorps

N° du produit ABIN7113781

Cet anticorps Lapin Polyclonal détecte spécifiquement ELL2 dans WB, ELISA et IP. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour ELL2 anticorps (ABIN7113781)

Antigène: ELL2 (Elongation Factor, RNA Polymerase II, 2 (ELL2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ELL2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Détail du produit anti-ELL2 anticorps

Fonction: ELL2 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: elongation factor, RNA polymerase II, 2

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur ELL2

Antigène: ELL2 (Elongation Factor, RNA Polymerase II, 2 (ELL2))

Autre désignation: ELL2

Sujet:

Synonyms: RNA polymerase II elongation factor ELL2|ELL2

Background: Elongation factor component of the super elongation complex(SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Component of the little elongation complex(LEC), a complex required to regulate small nuclear RNA(snRNA) gene transcription by RNA polymerase II and III(PubMed:22195968). Plays a role in immunoglobulin secretion in plasma cells: directs efficient alternative mRNA processing, influencing both proximal poly(A) site choice and exon skipping, as well as immunoglobulin heavy chain(IgH) alternative processing. Probably acts by regulating histone modifications accompanying transition from membrane-specific to secretory IgH mRNA expression.

Poids moléculaire: 72 kDa

ID gène: 22936

UniProt: O00472