COL18A1 anticorps

N° du produit ABIN7113812

L’anticorps anti-COL18A1 Polyclonal produit chez le Lapin a été validé pour WB, ELISA et IHC. Il convient pour la détection de COL18A1 dans des échantillons provenant de Humain. }

Aperçu rapide pour COL18A1 anticorps (ABIN7113812)

Antigène: COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COL18A1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-COL18A1 anticorps

Fonction: COL18A1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: collagen, type XVIII, alpha 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur COL18A1

Antigène: COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))

Autre désignation: COL18A1

Sujet:

Synonyms: Collagen alpha-1(XVIII) chain|Endostatin|Non-collagenous domain 1 (NC1)|COL18A1

Background: Endostatin is a naturally-occurring 20- kDa C-terminal fragment derived from COL18A1(also named as KNO). It is reported to serve as an anti-angiogenic agent, similar to angiostatin and thrombospondin. It potently inhibits endothelial cell proliferation and inhibits endothelial cell angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling. Endostatin is a broad spectrum angiogenesis inhibitor and may interfere with the pro-angiogenic action of growth factors such as basic fibroblast growth factor(bFGF/FGF-2) and vascular endothelial growth factor(VEGF).

Poids moléculaire: 19 kDa, 27 kDa

UniProt: P39060