ERLIN2 anticorps
Aperçu rapide pour ERLIN2 anticorps (ABIN7113871)
Antigène
Voir toutes ERLIN2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- ERLIN2 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- ER lipid raft associated 2
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- ERLIN2 (ER Lipid Raft Associated 2 (ERLIN2))
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Autre désignation
- ERLIN2
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Sujet
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Synonyms: Erlin-2|Endoplasmic reticulum lipid raft-associated protein 2|Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2 (SPFH domain-containing protein 2)|ERLIN2|C8orf2|SPFH2
Background: Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation(ERAD) of inositol 1,4,5-trisphosphate receptors(IP3Rs) such as ITPR1(PubMed:19240031, PubMed:17502376). Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex(PubMed:21343306). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex(PubMed:24217618).
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Poids moléculaire
- 38 kDa
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ID gène
- 11160
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UniProt
- O94905
Antigène
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