ERLIN2 anticorps

N° du produit ABIN7113871

Détail du produit anti-ERLIN2 anticorps

Antigène: ERLIN2 (ER Lipid Raft Associated 2 (ERLIN2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERLIN2 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: ER lipid raft associated 2

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur ERLIN2

Antigène: ERLIN2 (ER Lipid Raft Associated 2 (ERLIN2))

Autre désignation: ERLIN2 (ERLIN2 Produits)

Synonymes: anticorps C8orf2, anticorps Erlin-2, anticorps NET32, anticorps SPFH2, anticorps SPG18, anticorps BC036333, anticorps C87251, anticorps Spfh2, anticorps Erlin-2-B, anticorps erlin1, anticorps spfh1, anticorps spfh2, anticorps spfh2-B, anticorps RGD1309010, anticorps SPFH domain-containing protein 2-A, anticorps erlin2, anticorps erlin2-a, anticorps erlin2-b, anticorps spfh2-A, anticorps ER lipid raft associated 2, anticorps erlin-2, anticorps Erlin-2, anticorps ER lipid raft associated 2 S homeolog, anticorps ER lipid raft associated 2 L homeolog, anticorps ERLIN2, anticorps erlin2, anticorps Tsp_03442, anticorps erln2, anticorps Erlin2, anticorps erlin2.S, anticorps erlin2.L

Sujet: Synonyms:C8orf2, SPFH2 Background:Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation(ERAD) of inositol 1,4,5-trisphosphate receptors(IP3Rs) such as ITPR1(PubMed:19240031, PubMed:17502376). Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex(PubMed:21343306). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex(PubMed:24217618).

Poids moléculaire: 38 kDa

ID gène: 11160

UniProt: O94905