EIF3S1 anticorps
Aperçu rapide pour EIF3S1 anticorps (ABIN7113950)
Antigène
Voir toutes EIF3S1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- EIF3J antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- eukaryotic translation initiation factor 3, subunit J
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- EIF3S1 (Eukaryotic Translation Initiation Factor 3 Subunit J (EIF3S1))
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Autre désignation
- EIF3J
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Sujet
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Synonyms: Eukaryotic translation initiation factor 3 subunit J (eIF3j)|Eukaryotic translation initiation factor 3 subunit 1|eIF-3-alpha|eIF3 p35|EIF3J|EIF3S1
Background: Component of the eukaryotic translation initiation factor 3(eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex(43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit binds directly within the mRNA entry channel of the 40S ribosome to the aminoacyl(A) site. It may regulate the interaction between the 43S PIC and mRNA.
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Poids moléculaire
- 35 kDa
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ID gène
- 8669
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UniProt
- O75822
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Pathways
- Ribonucleoprotein Complex Subunit Organization
Antigène
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