EIF5A anticorps

N° du produit ABIN7113978

Cet anticorps anti-EIF5A est un anticorps Lapin Polyclonal détectant EIF5A dans WB, ELISA, IHC et IF. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour EIF5A anticorps (ABIN7113978)

Antigène: EIF5A (Eukaryotic Translation Initiation Factor 5A (EIF5A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF5A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-EIF5A anticorps

Fonction: EIF5A antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: eukaryotic translation initiation factor 5A

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur EIF5A

Antigène: EIF5A (Eukaryotic Translation Initiation Factor 5A (EIF5A))

Autre désignation: EIF5A

Sujet:

Synonyms: Eukaryotic translation initiation factor 5A-1 (eIF-5A-1, eIF-5A1)|Eukaryotic initiation factor 5A isoform 1 (eIF-5A)|Rev-binding factor|eIF-4D|EIF5A

Background: mRNA-binding protein involved in translation elongation. Has an important function at the level of Mrna turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.

Poids moléculaire: 17 kDa

ID gène: 1984

UniProt: P63241

Pathways: Regulation of Muscle Cell Differentiation