EXD2 anticorps (AA 400-621)
Aperçu rapide pour EXD2 anticorps (AA 400-621) (ABIN7114003)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 400-621
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Fonction
- EXD2 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
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Immunogen sequence: 400-621aa
Immunogen: exonuclease 3'-5' domain containing 2
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- EXD2 (Exonuclease 3'-5' Domain Containing 2 (EXD2))
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Autre désignation
- EXD2
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Sujet
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Synonyms: Exonuclease 3'-5' domain-containing protein 2|3'-5' exoribonuclease EXD2|Exonuclease 3'-5' domain-like-containing protein 2|EXD2|C14orf114|EXDL2
Background: Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.
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Poids moléculaire
- 56 kDa
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ID gène
- 55218
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UniProt
- Q9NVH0
Antigène
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