EYA4 anticorps
Aperçu rapide pour EYA4 anticorps (ABIN7114031)
Antigène
Voir toutes EYA4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- EYA4 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- eyes absent homolog 4(Drosophila)
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000, IF: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- EYA4 (Eyes Absent Homolog 4 (EYA4))
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Autre désignation
- EYA4
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Sujet
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Synonyms: Eyes absent homolog 4|EYA4
Background: Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX(H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. May be involved in development of the eye(By similarity).
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Poids moléculaire
- 67 kDa
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ID gène
- 2070
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UniProt
- O95677
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Pathways
- Sensory Perception of Sound
Antigène
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