F-Box Protein 3 anticorps

N° du produit ABIN7114048

Cet anticorps Lapin Polyclonal détecte spécifiquement F-Box Protein 3 dans ELISA et WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour F-Box Protein 3 anticorps (ABIN7114048)

Antigène: F-Box Protein 3 (FBXO3)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp F-Box Protein 3 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-F-Box Protein 3 anticorps

Fonction: FBXO3 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: F-box protein 3

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur F-Box Protein 3

Antigène: F-Box Protein 3 (FBXO3)

Autre désignation: FBXO3

Sujet:

Synonyms: F-box only protein 3|FBXO3|FBX3

Background: Substrate recognition component of the SCF(SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation.

Poids moléculaire: 48-50 kDa

ID gène: 26273

UniProt: Q9UK99